I first encountered the first coming of The Second Coming in Groundhog Day (or at least I thought so), and the second coming of The Second Coming in Heroes.

And when I searched my videos, I couldn't find The Second Coming in Groundhog Day. Strangely, I seem to remember hearing Sam's voice say "The best lack all conviction while the worst are full of passionate intensity"

Sigh... Still searching for it.

[Edit 20 June 2012, 10:40]

And I've found it, with the help of Subscene. It's from Season 2, Episode 6 of Quantum Leap, Good Morning Peora. It's at 31:22.